They will help with setting up for the event marshalling the route and clearing up the area afterwards.
The Ramathon will start and finish at Pride Park Stadium and Derby County Football Club is again the race partner for the event. The route then includes the city centre and Elvaston Castle Country Park. Derby College Assessor Ed Watkins explained: "We have been involved in this and many other annual events for several years and it is part of an ongoing programme of work experience for the students.
"Many of our students are planning careers in the public services including the Army and Police and in the security industry so the problem solving skills that they have gained will be invaluable in their future careers.
Ramathon Race Director Richard Kay said: "We have a fantastic relationship with Derby College and are very grateful for their support again this year.
"The students' role on the day is invaluable - ensuring that the runners have safe passage around the route and that the thousands of spectators are able to enjoy the action and cheer on their family and friends."
To enter online and for further information visit www.ramathon.co.uk